ctms/backend/app/api/v1/visits.py

import uuid

from fastapi import APIRouter, Depends, HTTPException, status
from sqlalchemy.ext.asyncio import AsyncSession

from app.core.deps import get_current_user, get_db_session, require_study_member, require_study_roles, require_study_not_locked
from app.crud import audit as audit_crud
from app.crud import site as site_crud
from app.crud import subject as subject_crud
from app.crud import study as study_crud
from app.crud import visit as visit_crud
from app.schemas.subject import SubjectUpdate
from app.schemas.visit import EarlyTerminationCreate, VisitCreate, VisitRead, VisitUpdate

router = APIRouter()


async def _ensure_subject(db: AsyncSession, study_id: uuid.UUID, subject_id: uuid.UUID):
    subject = await subject_crud.get_subject(db, subject_id)
    if not subject or subject.study_id != study_id:
        raise HTTPException(status_code=status.HTTP_404_NOT_FOUND, detail="参与者不存在")
    return subject


async def _ensure_subject_active(db: AsyncSession, subject) -> None:
    if not subject or not subject.site_id:
        return
    site = await site_crud.get_site(db, subject.site_id)
    if not site or not site.is_active:
        raise HTTPException(status_code=status.HTTP_403_FORBIDDEN, detail="中心已停用")


@router.get(
    "/",
    response_model=list[VisitRead],
    dependencies=[Depends(require_study_member())],
)
async def list_visits(
    study_id: uuid.UUID,
    subject_id: uuid.UUID,
    db: AsyncSession = Depends(get_db_session),
) -> list[VisitRead]:
    await _ensure_subject(db, study_id, subject_id)
    await visit_crud.mark_overdue_as_lost(db, subject_id)
    visits = await visit_crud.list_visits(db, subject_id)
    return list(visits)


@router.post(
    "/",
    response_model=VisitRead,
    status_code=status.HTTP_201_CREATED,
    dependencies=[Depends(require_study_roles(["PM", "CRA"])), Depends(require_study_not_locked())],
)
async def create_visit(
    study_id: uuid.UUID,
    subject_id: uuid.UUID,
    visit_in: VisitCreate,
    db: AsyncSession = Depends(get_db_session),
    current_user=Depends(get_current_user),
) -> VisitRead:
    subject = await _ensure_subject(db, study_id, subject_id)
    await _ensure_subject_active(db, subject)
    if visit_in.subject_id != subject_id:
        raise HTTPException(status_code=status.HTTP_400_BAD_REQUEST, detail="参与者不匹配")
    if visit_in.window_start and visit_in.window_end and visit_in.window_start > visit_in.window_end:
        raise HTTPException(status_code=status.HTTP_400_BAD_REQUEST, detail="访视窗口结束日期不能早于开始日期")
    if (
        visit_in.planned_date
        and visit_in.window_start
        and visit_in.planned_date < visit_in.window_start
    ):
        raise HTTPException(status_code=status.HTTP_400_BAD_REQUEST, detail="计划访视日期不能早于访视窗口开始日期")
    if (
        visit_in.planned_date
        and visit_in.window_end
        and visit_in.planned_date > visit_in.window_end
    ):
        raise HTTPException(status_code=status.HTTP_400_BAD_REQUEST, detail="计划访视日期不能晚于访视窗口结束日期")
    next_visit_code = await visit_crud.get_next_visit_code(db, subject_id)
    if next_visit_code == "V1" and not visit_in.planned_date:
        raise HTTPException(status_code=status.HTTP_400_BAD_REQUEST, detail="首次新增访视必须填写计划访视日期")
    visit = await visit_crud.create_visit(
        db,
        study_id=study_id,
        visit_in=visit_in,
        subject=subject,
        visit_code=next_visit_code,
        planned_date=visit_in.planned_date,
    )
    if next_visit_code == "V1" and visit_in.planned_date:
        study = await study_crud.get(db, study_id)
        if study:
            await visit_crud.create_scheduled_visits(
                db,
                study_id=study_id,
                subject=subject,
                base_date=visit_in.planned_date,
                visit_schedule=study.visit_schedule,
            )
    await audit_crud.log_action(
        db,
        study_id=study_id,
        entity_type="visit",
        entity_id=visit.id,
        action="CREATE_VISIT",
        detail=f"访视 {visit.visit_code} 已创建",
        operator_id=current_user.id,
        operator_role=current_user.role,
    )
    return visit


@router.post(
    "/early-termination",
    response_model=VisitRead,
    status_code=status.HTTP_201_CREATED,
    dependencies=[Depends(require_study_roles(["PM", "CRA"])), Depends(require_study_not_locked())],
)
async def create_early_termination(
    study_id: uuid.UUID,
    subject_id: uuid.UUID,
    termination_in: EarlyTerminationCreate,
    db: AsyncSession = Depends(get_db_session),
    current_user=Depends(get_current_user),
) -> VisitRead:
    subject = await _ensure_subject(db, study_id, subject_id)
    await _ensure_subject_active(db, subject)
    reason = termination_in.reason.strip()
    if not reason:
        raise HTTPException(status_code=status.HTTP_400_BAD_REQUEST, detail="提前终止原因不能为空")
    if subject.baseline_date and termination_in.termination_date < subject.baseline_date:
        raise HTTPException(status_code=status.HTTP_400_BAD_REQUEST, detail="提前终止日期不能早于基线/治疗日期")

    try:
        visit = await visit_crud.create_early_termination_visit(
            db,
            study_id=study_id,
            subject=subject,
            termination_date=termination_in.termination_date,
            reason=reason,
            notes=termination_in.notes,
        )
    except ValueError as exc:
        raise HTTPException(status_code=status.HTTP_400_BAD_REQUEST, detail=str(exc)) from exc
    await subject_crud.update_subject(
        db,
        subject,
        SubjectUpdate(
            status="DROPPED",
            completion_date=termination_in.termination_date,
            drop_reason=reason,
        ),
    )
    await audit_crud.log_action(
        db,
        study_id=study_id,
        entity_type="visit",
        entity_id=visit.id,
        action="CREATE_EARLY_TERMINATION",
        detail=f"参与者 {subject.subject_no} 已提前终止",
        operator_id=current_user.id,
        operator_role=current_user.role,
    )
    return visit


@router.patch(
    "/{visit_id}",
    response_model=VisitRead,
    dependencies=[Depends(require_study_roles(["PM", "CRA"])), Depends(require_study_not_locked())],
)
async def update_visit(
    study_id: uuid.UUID,
    subject_id: uuid.UUID,
    visit_id: uuid.UUID,
    visit_in: VisitUpdate,
    db: AsyncSession = Depends(get_db_session),
    current_user=Depends(get_current_user),
) -> VisitRead:
    subject = await _ensure_subject(db, study_id, subject_id)
    await _ensure_subject_active(db, subject)
    visit = await visit_crud.get_visit(db, visit_id)
    if not visit or visit.subject_id != subject_id or visit.study_id != study_id:
        raise HTTPException(status_code=status.HTTP_404_NOT_FOUND, detail="访视不存在")
    if visit_in.status == "DONE" and not visit_in.actual_date:
        raise HTTPException(status_code=status.HTTP_400_BAD_REQUEST, detail="状态为已完成时必须填写实际日期")
    if visit.window_start and visit.window_end and visit.window_start > visit.window_end:
        raise HTTPException(status_code=status.HTTP_400_BAD_REQUEST, detail="当前访视窗口配置异常，请先修复窗口日期")
    if visit_in.actual_date and visit.window_start and visit_in.actual_date < visit.window_start:
        raise HTTPException(status_code=status.HTTP_400_BAD_REQUEST, detail="实际访视日期不能早于访视窗口开始日期")
    if visit_in.actual_date and visit.window_end and visit_in.actual_date > visit.window_end:
        raise HTTPException(status_code=status.HTTP_400_BAD_REQUEST, detail="实际访视日期不能晚于访视窗口结束日期")
    updated = await visit_crud.update_visit(db, visit, visit_in)
    detail = None
    if visit_in.status:
        detail = f"访视 {visit.visit_code} {visit.status} -> {visit_in.status}"
    await audit_crud.log_action(
        db,
        study_id=study_id,
        entity_type="visit",
        entity_id=visit_id,
        action="VISIT_STATUS_CHANGE" if detail else "UPDATE_VISIT",
        detail=detail or "访视已更新",
        operator_id=current_user.id,
        operator_role=current_user.role,
    )
    return updated


@router.delete(
    "/{visit_id}",
    status_code=status.HTTP_204_NO_CONTENT,
    dependencies=[Depends(require_study_roles(["PM", "CRA"])), Depends(require_study_not_locked())],
)
async def delete_visit(
    study_id: uuid.UUID,
    subject_id: uuid.UUID,
    visit_id: uuid.UUID,
    db: AsyncSession = Depends(get_db_session),
    current_user=Depends(get_current_user),
) -> None:
    subject = await _ensure_subject(db, study_id, subject_id)
    await _ensure_subject_active(db, subject)
    visit = await visit_crud.get_visit(db, visit_id)
    if not visit or visit.subject_id != subject_id or visit.study_id != study_id:
        raise HTTPException(status_code=status.HTTP_404_NOT_FOUND, detail="访视不存在")
    await visit_crud.delete_visit(db, visit)
    await audit_crud.log_action(
        db,
        study_id=study_id,
        entity_type="visit",
        entity_id=visit_id,
        action="DELETE_VISIT",
        detail=f"访视 {visit_id} 已删除",
        operator_id=current_user.id,
        operator_role=current_user.role,
    )