diff --git a/frontend/src/api/sites.ts b/frontend/src/api/sites.ts
new file mode 100644
index 00000000..5682b81f
--- /dev/null
+++ b/frontend/src/api/sites.ts
@@ -0,0 +1,5 @@
+import { apiGet } from "./axios";
+import type { ApiListResponse } from "../types/api";
+
+export const fetchSites = (studyId: string) =>
+  apiGet<ApiListResponse<any>>(`/api/v1/studies/${studyId}/sites/`);
diff --git a/frontend/src/api/subjects.ts b/frontend/src/api/subjects.ts
new file mode 100644
index 00000000..1b38570f
--- /dev/null
+++ b/frontend/src/api/subjects.ts
@@ -0,0 +1,11 @@
+import { apiGet, apiPost, apiPatch } from "./axios";
+import type { ApiListResponse } from "../types/api";
+
+export const fetchSubjects = (studyId: string, params?: Record<string, any>) =>
+  apiGet<ApiListResponse<any>>(`/api/v1/studies/${studyId}/subjects/`, { params });
+
+export const createSubject = (studyId: string, payload: Record<string, any>) =>
+  apiPost(`/api/v1/studies/${studyId}/subjects/`, payload);
+
+export const updateSubject = (studyId: string, subjectId: string, payload: Record<string, any>) =>
+  apiPatch(`/api/v1/studies/${studyId}/subjects/${subjectId}`, payload);
diff --git a/frontend/src/api/visits.ts b/frontend/src/api/visits.ts
new file mode 100644
index 00000000..1b36b92f
--- /dev/null
+++ b/frontend/src/api/visits.ts
@@ -0,0 +1,7 @@
+import { apiGet, apiPatch } from "./axios";
+
+export const fetchVisits = (studyId: string, subjectId: string) =>
+  apiGet(`/api/v1/studies/${studyId}/subjects/${subjectId}/visits/`);
+
+export const updateVisit = (studyId: string, subjectId: string, visitId: string, payload: Record<string, any>) =>
+  apiPatch(`/api/v1/studies/${studyId}/subjects/${subjectId}/visits/${visitId}`, payload);
diff --git a/frontend/src/components/Layout.vue b/frontend/src/components/Layout.vue
index bb9a73de..47c934c9 100644
--- a/frontend/src/components/Layout.vue
+++ b/frontend/src/components/Layout.vue
@@ -19,6 +19,7 @@
         <el-menu-item index="/study/home">项目首页</el-menu-item>
         <el-menu-item index="/study/milestones">里程碑</el-menu-item>
         <el-menu-item index="/study/tasks">任务</el-menu-item>
+        <el-menu-item index="/study/subjects">受试者</el-menu-item>
       </el-menu>
     </el-aside>
     <el-main>
diff --git a/frontend/src/components/SubjectForm.vue b/frontend/src/components/SubjectForm.vue
new file mode 100644
index 00000000..b7a9b72b
--- /dev/null
+++ b/frontend/src/components/SubjectForm.vue
@@ -0,0 +1,83 @@
+<template>
+  <el-dialog title="新增受试者" v-model="visible" width="520px" @close="onClose">
+    <el-form ref="formRef" :model="form" :rules="rules" label-width="100px">
+      <el-form-item label="中心" prop="site_id">
+        <el-select v-model="form.site_id" placeholder="请选择" filterable>
+          <el-option v-for="s in sites" :key="s.id" :label="s.name || s.id" :value="s.id" />
+        </el-select>
+      </el-form-item>
+      <el-form-item label="受试者编号" prop="subject_no">
+        <el-input v-model="form.subject_no" />
+      </el-form-item>
+      <el-form-item label="筛选日期" prop="screening_date">
+        <el-date-picker v-model="form.screening_date" type="date" value-format="YYYY-MM-DD" placeholder="选择日期" />
+      </el-form-item>
+    </el-form>
+    <template #footer>
+      <el-button @click="onClose">取消</el-button>
+      <el-button type="primary" :loading="submitting" @click="onSubmit">提交</el-button>
+    </template>
+  </el-dialog>
+</template>
+
+<script setup lang="ts">
+import { computed, reactive, ref } from "vue";
+import type { FormInstance, FormRules } from "element-plus";
+import { ElMessage } from "element-plus";
+import { createSubject } from "../api/subjects";
+import { useStudyStore } from "../store/study";
+
+interface Props {
+  modelValue: boolean;
+  sites: any[];
+}
+
+const props = defineProps<Props>();
+const emit = defineEmits(["update:modelValue", "success"]);
+
+const visible = computed({
+  get: () => props.modelValue,
+  set: (v: boolean) => emit("update:modelValue", v),
+});
+
+const formRef = ref<FormInstance>();
+const submitting = ref(false);
+const study = useStudyStore();
+
+const form = reactive({
+  site_id: "",
+  subject_no: "",
+  screening_date: "",
+});
+
+const rules: FormRules = {
+  site_id: [{ required: true, message: "请选择中心", trigger: "change" }],
+  subject_no: [{ required: true, message: "请输入受试者编号", trigger: "blur" }],
+};
+
+const onClose = () => {
+  visible.value = false;
+};
+
+const onSubmit = async () => {
+  if (!formRef.value) return;
+  await formRef.value.validate(async (valid) => {
+    if (!valid) return;
+    if (!study.currentStudy) {
+      ElMessage.error("未选择项目");
+      return;
+    }
+    submitting.value = true;
+    try {
+      await createSubject(study.currentStudy.id, { ...form });
+      ElMessage.success("提交成功");
+      emit("success");
+      onClose();
+    } catch (e: any) {
+      ElMessage.error(e?.response?.data?.message || "提交失败");
+    } finally {
+      submitting.value = false;
+    }
+  });
+};
+</script>
diff --git a/frontend/src/components/VisitTable.vue b/frontend/src/components/VisitTable.vue
new file mode 100644
index 00000000..5734aa56
--- /dev/null
+++ b/frontend/src/components/VisitTable.vue
@@ -0,0 +1,72 @@
+<template>
+  <el-card>
+    <div class="header">
+      <h4>访视计划</h4>
+    </div>
+    <el-table :data="visits" style="width: 100%" v-loading="loading">
+      <el-table-column prop="visit_code" label="代码" width="120" />
+      <el-table-column prop="visit_name" label="名称" />
+      <el-table-column prop="planned_date" label="计划日期" width="140" />
+      <el-table-column prop="actual_date" label="实际日期" width="140" />
+      <el-table-column prop="status" label="状态" width="120" />
+      <el-table-column v-if="canEdit" label="操作" width="200">
+        <template #default="scope">
+          <el-button type="primary" link size="small" @click="markDone(scope.row)">标记完成</el-button>
+          <el-button type="danger" link size="small" @click="markMissed(scope.row)">标记缺失</el-button>
+        </template>
+      </el-table-column>
+    </el-table>
+  </el-card>
+</template>
+
+<script setup lang="ts">
+import { ref } from "vue";
+import { ElMessage, ElMessageBox } from "element-plus";
+import { updateVisit } from "../api/visits";
+import { useStudyStore } from "../store/study";
+
+interface Props {
+  visits: any[];
+  subjectId: string;
+  canEdit: boolean;
+  onRefresh: () => void;
+}
+
+const props = defineProps<Props>();
+const study = useStudyStore();
+const loading = ref(false);
+
+const doUpdate = async (visitId: string, payload: Record<string, any>) => {
+  if (!study.currentStudy) return;
+  loading.value = true;
+  try {
+    await updateVisit(study.currentStudy.id, props.subjectId, visitId, payload);
+    ElMessage.success("更新成功");
+    props.onRefresh();
+  } catch (e: any) {
+    ElMessage.error(e?.response?.data?.message || "更新失败");
+  } finally {
+    loading.value = false;
+  }
+};
+
+const markDone = async (row: any) => {
+  await ElMessageBox.confirm("确认标记为完成？", "提示");
+  const today = new Date().toISOString().slice(0, 10);
+  doUpdate(row.id, { status: "DONE", actual_date: today });
+};
+
+const markMissed = async (row: any) => {
+  await ElMessageBox.confirm("确认标记为缺失？", "提示");
+  doUpdate(row.id, { status: "MISSED", actual_date: null });
+};
+</script>
+
+<style scoped>
+.header {
+  display: flex;
+  align-items: center;
+  justify-content: space-between;
+  margin-bottom: 8px;
+}
+</style>
diff --git a/frontend/src/router/index.ts b/frontend/src/router/index.ts
index 96e4f5f8..282c31ea 100644
--- a/frontend/src/router/index.ts
+++ b/frontend/src/router/index.ts
@@ -9,6 +9,7 @@ import StudyHome from "../views/StudyHome.vue";
 import Tasks from "../views/Tasks.vue";
 import Milestones from "../views/Milestones.vue";
 import Subjects from "../views/Subjects.vue";
+import SubjectDetail from "../views/SubjectDetail.vue";
 import Aes from "../views/Aes.vue";
 import DataQueries from "../views/DataQueries.vue";
 import Imp from "../views/Imp.vue";
@@ -57,6 +58,12 @@ const routes: RouteRecordRaw[] = [
         component: Subjects,
         meta: { title: "受试者", requiresStudy: true },
       },
+      {
+        path: "study/subjects/:subjectId",
+        name: "StudySubjectDetail",
+        component: SubjectDetail,
+        meta: { title: "受试者详情", requiresStudy: true },
+      },
       {
         path: "study/aes",
         name: "StudyAes",
diff --git a/frontend/src/views/SubjectDetail.vue b/frontend/src/views/SubjectDetail.vue
new file mode 100644
index 00000000..225db51b
--- /dev/null
+++ b/frontend/src/views/SubjectDetail.vue
@@ -0,0 +1,103 @@
+<template>
+  <div class="page" v-if="subject">
+    <el-card class="mb-12">
+      <h3>受试者 {{ subject.subject_no }}</h3>
+      <p>中心：{{ subject.site_id }}</p>
+      <p>状态：{{ subject.status }}</p>
+      <div v-if="canEdit" class="actions">
+        <el-button size="small" type="primary" @click="setStatus('ENROLLED')">标记入组</el-button>
+        <el-button size="small" type="success" @click="setStatus('COMPLETED')">标记完成</el-button>
+        <el-button size="small" type="danger" @click="setStatus('DROPPED')">标记脱落</el-button>
+      </div>
+    </el-card>
+
+    <VisitTable :visits="visits" :subject-id="subject.id" :can-edit="canEdit" :on-refresh="loadVisits" />
+  </div>
+  <div v-else class="page">
+    <el-skeleton rows="3" animated />
+  </div>
+</template>
+
+<script setup lang="ts">
+import { onMounted, ref, computed } from "vue";
+import { useRoute } from "vue-router";
+import { ElMessage, ElMessageBox } from "element-plus";
+import { fetchSubjects, updateSubject } from "../api/subjects";
+import { fetchVisits } from "../api/visits";
+import { useStudyStore } from "../store/study";
+import { useAuthStore } from "../store/auth";
+import VisitTable from "../components/VisitTable.vue";
+
+const route = useRoute();
+const study = useStudyStore();
+const auth = useAuthStore();
+
+const subject = ref<any | null>(null);
+const visits = ref<any[]>([]);
+
+const canEdit = computed(() => {
+  const role = auth.user?.role;
+  return role === "ADMIN" || role === "PM" || role === "CRA";
+});
+
+const loadSubject = async () => {
+  if (!study.currentStudy) return;
+  try {
+    const subjectId = route.params.subjectId as string;
+    const { data } = await fetchSubjects(study.currentStudy.id, { skip: 0, limit: 1000 });
+    const list = data.items || data || [];
+    subject.value = list.find((s: any) => s.id === subjectId) || null;
+  } catch (e: any) {
+    ElMessage.error(e?.response?.data?.message || "受试者加载失败");
+  }
+};
+
+const loadVisits = async () => {
+  if (!study.currentStudy || !route.params.subjectId) return;
+  try {
+    const { data } = await fetchVisits(study.currentStudy.id, route.params.subjectId as string);
+    visits.value = data.items || data;
+  } catch (e: any) {
+    ElMessage.error(e?.response?.data?.message || "访视加载失败");
+  }
+};
+
+const setStatus = async (status: string) => {
+  await ElMessageBox.confirm(`确认将受试者状态设置为 ${status}？`, "提示");
+  if (!study.currentStudy || !subject.value) return;
+  const payload: Record<string, any> = { status };
+  if (status == "ENROLLED") payload.enrollment_date = new Date().toISOString().slice(0, 10);
+  if (status == "COMPLETED") payload.completion_date = new Date().toISOString().slice(0, 10);
+  if (status == "DROPPED") payload.drop_reason = "Dropped";
+  try {
+    await updateSubject(study.currentStudy.id, subject.value.id, payload);
+    ElMessage.success("状态已更新");
+    await loadSubject();
+    await loadVisits();
+  } catch (e: any) {
+    ElMessage.error(e?.response?.data?.message || "更新失败");
+  }
+};
+
+onMounted(async () => {
+  if (!auth.user && auth.token) {
+    await auth.fetchMe().catch(() => {});
+  }
+  await loadSubject();
+  await loadVisits();
+});
+</script>
+
+<style scoped>
+.page {
+  padding: 16px;
+}
+.actions {
+  display: flex;
+  gap: 8px;
+  margin-top: 8px;
+}
+.mb-12 {
+  margin-bottom: 12px;
+}
+</style>
diff --git a/frontend/src/views/Subjects.vue b/frontend/src/views/Subjects.vue
index eff5b545..fd14622f 100644
--- a/frontend/src/views/Subjects.vue
+++ b/frontend/src/views/Subjects.vue
@@ -1,13 +1,152 @@
 <template>
   <div class="page">
-    <el-card><h2>受试者</h2></el-card>
+    <el-card class="mb-12">
+      <div class="filters">
+        <el-select
+          v-model="filters.site_id"
+          placeholder="中心"
+          clearable
+          filterable
+          style="width: 200px"
+          @change="loadSubjects"
+        >
+          <el-option v-for="s in sites" :key="s.id" :label="s.name || s.id" :value="s.id" />
+        </el-select>
+        <el-select v-model="filters.status" placeholder="状态" clearable @change="loadSubjects">
+          <el-option v-for="s in statuses" :key="s" :label="s" :value="s" />
+        </el-select>
+        <div class="spacer" />
+        <el-button type="primary" v-if="canEdit" @click="showForm = true">新增受试者</el-button>
+      </div>
+    </el-card>
+
+    <el-card>
+      <el-table :data="subjects" v-loading="loading" style="width: 100%" @row-click="goDetail">
+        <el-table-column prop="subject_no" label="受试者编号" />
+        <el-table-column prop="site_id" label="中心ID" />
+        <el-table-column prop="status" label="状态" width="120" />
+        <el-table-column prop="screening_date" label="筛选日期" width="140" />
+        <el-table-column prop="enrollment_date" label="入组日期" width="140" />
+      </el-table>
+      <el-pagination
+        class="pagination"
+        layout="prev, pager, next"
+        :page-size="pageSize"
+        :current-page="page"
+        :total="total"
+        @current-change="onPageChange"
+      />
+    </el-card>
+
+    <SubjectForm v-model="showForm" :sites="sites" @success="loadSubjects" />
   </div>
 </template>
 
-<script setup lang="ts"></script>
+<script setup lang="ts">
+import { computed, onMounted, ref } from "vue";
+import { useRouter } from "vue-router";
+import { ElMessage } from "element-plus";
+import { fetchSubjects } from "../api/subjects";
+import { fetchSites } from "../api/sites";
+import { useStudyStore } from "../store/study";
+import { useAuthStore } from "../store/auth";
+import SubjectForm from "../components/SubjectForm.vue";
+
+const study = useStudyStore();
+const auth = useAuthStore();
+const router = useRouter();
+
+const subjects = ref<any[]>([]);
+const sites = ref<any[]>([]);
+const loading = ref(false);
+const total = ref(0);
+const page = ref(1);
+const pageSize = 10;
+
+const statuses = ["SCREENING", "ENROLLED", "COMPLETED", "DROPPED"];
+
+const filters = ref({
+  site_id: "",
+  status: "",
+});
+
+const showForm = ref(false);
+
+const canEdit = computed(() => {
+  const role = auth.user?.role;
+  return role === "ADMIN" || role === "PM" || role === "CRA";
+});
+
+const loadSubjects = async () => {
+  if (!study.currentStudy) return;
+  loading.value = true;
+  try {
+    const params: Record<string, any> = {
+      skip: (page.value - 1) * pageSize,
+      limit: pageSize,
+    };
+    if (filters.value.site_id) params.site_id = filters.value.site_id;
+    if (filters.value.status) params.status = filters.value.status;
+    const { data } = await fetchSubjects(study.currentStudy.id, params);
+    if (Array.isArray(data)) {
+      subjects.value = data;
+      total.value = data.length;
+    } else {
+      subjects.value = data.items || [];
+      total.value = data.total || subjects.value.length;
+    }
+  } catch (e: any) {
+    ElMessage.error(e?.response?.data?.message || "受试者加载失败");
+  } finally {
+    loading.value = false;
+  }
+};
+
+const onPageChange = (p: number) => {
+  page.value = p;
+  loadSubjects();
+};
+
+const goDetail = (row: any) => {
+  router.push(`/study/subjects/${row.id}`);
+};
+
+const loadSites = async () => {
+  if (!study.currentStudy) return;
+  try {
+    const { data } = await fetchSites(study.currentStudy.id);
+    sites.value = data.items || data;
+  } catch {
+    // ignore
+  }
+};
+
+onMounted(async () => {
+  if (!auth.user && auth.token) {
+    await auth.fetchMe().catch(() => {});
+  }
+  await loadSites();
+  loadSubjects();
+});
+</script>
 
 <style scoped>
 .page {
   padding: 16px;
 }
+.filters {
+  display: flex;
+  gap: 8px;
+  align-items: center;
+}
+.spacer {
+  flex: 1;
+}
+.pagination {
+  margin-top: 12px;
+  text-align: right;
+}
+.mb-12 {
+  margin-bottom: 12px;
+}
 </style>
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