优化文档管理与导航体验

1、为文档增加编辑接口和前端编辑抽屉，文档列表与详情页统一按创建、更新、删除权限展示操作。

2、将文档版本上传和分发改为抽屉交互，并在详情页补充版本删除权限检查。

3、增强全局面包屑上下文和详情页标题同步，避免详情页重复或缺失导航信息。

4、按项目权限过滤快捷入口、首页费用指标和 eTMF 新建入口，并补充对应前端测试。

backend/app/services/document_service.py

@@ -32,7 +32,7 @@ from app.models.document import Document, DocumentScopeType, DocumentStatus
 from app.models.document_version import DocumentVersion, DocumentVersionStatus
 from app.schemas.acknowledgement import AcknowledgementCreate
 from app.schemas.distribution import DistributionCreate, DistributionRead, DistributionStats
-from app.schemas.document import DocumentCreate, DocumentDetail, DocumentSummary
+from app.schemas.document import DocumentCreate, DocumentDetail, DocumentSummary, DocumentUpdate
 from app.schemas.document_version import DocumentVersionRead, DocumentVersionSummary
 from app.schemas.notification import NotificationItem
 from app.schemas.user import UserDisplay
@@ -43,6 +43,7 @@ DOCUMENT_ACTION_PERMISSIONS = {
     "view": "documents:read",
     "ack": "documents:read",
     "create_document": "documents:create",
+    "update_document": "documents:update",
     "create_version": "documents:update",
     "distribute": "documents:update",
     "delete_document": "documents:delete",
@@ -261,6 +262,56 @@ async def get_document_detail(
     )
 
 
+async def update_document(
+    db: AsyncSession,
+    document_id: uuid.UUID,
+    doc_in: DocumentUpdate,
+    current_user,
+) -> Document:
+    doc = await document_crud.get(db, document_id)
+    if not doc:
+        raise HTTPException(status_code=status.HTTP_404_NOT_FOUND, detail="文档不存在")
+    await _ensure_study_access(db, doc.trial_id, current_user, action="update_document")
+
+    values = doc_in.model_dump(exclude_unset=True)
+    if not values:
+        return doc
+
+    next_scope = values.get("scope_type", doc.scope_type)
+    next_scope_value = getattr(next_scope, "value", next_scope)
+    next_site_id = values.get("site_id", doc.site_id)
+    if next_scope_value == DocumentScopeType.SITE.value:
+        if not next_site_id:
+            raise HTTPException(status_code=status.HTTP_422_UNPROCESSABLE_ENTITY, detail="分中心文件需指定分中心")
+        site = await site_crud.get_site(db, next_site_id)
+        if not site or site.study_id != doc.trial_id:
+            raise HTTPException(status_code=status.HTTP_400_BAD_REQUEST, detail="分中心不属于当前项目")
+        if not site.is_active:
+            raise HTTPException(status_code=status.HTTP_400_BAD_REQUEST, detail="中心已停用")
+    else:
+        values["site_id"] = None
+
+    before = _doc_snapshot(doc)
+    await document_crud.update(db, document_id, values, commit=False)
+    updated = await document_crud.get(db, document_id)
+    if not updated:
+        raise HTTPException(status_code=status.HTTP_404_NOT_FOUND, detail="文档不存在")
+    db.add(
+        AuditLog(
+            study_id=updated.trial_id,
+            entity_type="DOCUMENT",
+            entity_id=updated.id,
+            action="DOCUMENT_UPDATED",
+            detail=_audit_detail(before, _doc_snapshot(updated)),
+            operator_id=current_user.id,
+            operator_role=await get_operator_role_label(db, updated.trial_id, current_user),
+        )
+    )
+    await db.commit()
+    await db.refresh(updated)
+    return updated
+
+
 async def create_version(
     db: AsyncSession,
     document_id: uuid.UUID,