细节优化——1

backend/app/crud/ae.py

@@ -52,7 +52,7 @@ async def create_ae(
         severity=ae_in.severity,
         causality=ae_in.causality,
         action_taken=None,
-        outcome=None,
+        outcome=ae_in.outcome,
         reported_to_sponsor=False,
         report_due_date=due_date,
         status="NEW",
@@ -96,8 +96,10 @@ async def list_ae(
     return result.scalars().all()
 
 
-async def update_ae(db: AsyncSession, ae: AdverseEvent, ae_in: AEUpdate) -> AdverseEvent:
+async def update_ae(db: AsyncSession, study_id: uuid.UUID, ae: AdverseEvent, ae_in: AEUpdate) -> AdverseEvent:
     update_data = ae_in.model_dump(exclude_unset=True)
+    if "subject_id" in update_data:
+        await _validate_site_subject(db, study_id, None, update_data["subject_id"])
     if "onset_date" in update_data or "seriousness" in update_data:
         onset = update_data.get("onset_date", ae.onset_date)
         seriousness = update_data.get("seriousness", ae.seriousness)